This study investigates economic structures, commuter patterns, and alternative mobility types, including electromobility, from the perspective of employers in the Czech–Bavarian border region, integrating quantitative data analysis with qualitative interview data provided by regional experts. The findings reveal persistent economic asymmetries motivating commuting flows, heavy reliance on private vehicles, and significant vulnerabilities exposed by recent border disruptions. Experts’ insights emphasize the strategic importance of cross-border labor and the urgent need for integrated transport and labor market policies. This research advances theoretical understanding by linking labor market and transport infrastructures and provides practical recommendations for sustainable cross-border cooperation in the future. The novelty of the conducted research lies in its combined methodological approach. It merges quantitative commuting data with qualitative insights from regional experts, thereby capturing both structural patterns and lived realities in the Czech–Bavarian border region. In addition, it provides an integrated analysis of economic-, pattern-, and transport-mode-related aspects, including electromobility, from the Bavarian employers’ standpoint. This offers a more holistic understanding of cross-border interdependencies.